Lingting S
- Research Program Mentor
PhD at Columbia University
Expertise
Immunology, Genetics, Single Cell RNA Seq, T cells, SAT Math, Math
Bio
I am a postdoctoral research scientist in the department of biomedical engineering at Columbia university studying the interaction of immune system and cancer via both computational and experimental approach. I received my Ph.D. degree at Columbia University in the department of biomedical engineering studying the mechanosensing of regulatory T cell induction. I obtained my BS degree in biomedical engineering at Rutgers University where I worked on developing an in vitro approach to identify skin sensitizers to eliminate animal cosmetic testing. I enjoy working on both the wet lab and dry lab part of research. My goal is to build my own lab to study the interaction between immune system and diseases. Outside of work, I enjoy many outdoor as well as indoor activities. My workouts are Zumba classes, biking, and hiking. Attending Broadway shows, watching sunsets by the Hudson River, and biking in the central park is the reason why I stayed in NYC.Project ideas
Adoptive therapy with Regulatory T cells
Regulatory T cells are a subset of T cells that suppress the immune response, and they hold the potential to treat autoimmune diseases, inflammatory diseases, and graph versus host diseases. The student can conduct literature searches on the application of regulatory T cells in adoptive therapy. It is exciting to learn about the current status, challenges, and future development of Treg adoptive therapy.
Pan-cancer signature identification with machine learning tools
The goal of this project is to analyze Single-cell RNA-Seq data of T cells in the blood samples of many cancer types to capture signature genes for the detection of cancer compared to healthy donors. The student will work on data collection, batch collection, RNA-Seq analysis, machine learning model building, and marker identification.
