Shruthi Inamdar

Correlation Between COVID-19 at Time of MI and Myocardial Infarction Mortality: A Meta-Analysis

Started June 21, 2024

Abstract or project description

This meta-analysis explores the correlation between COVID-19 positivity and myocardial infarction (MI) mortality, examining why MI mortality rates increased during the pandemic. Three studies and 87,534 patients were included after screening 112 results from a PubMed search on June 7th, 2024. Patients across the three studies shared cofactors of MI, including smoking, diabetes, hyperlipidemia, and hypertension. The average risk ratio was 2.97, and the confidence interval was 1.98 to 4.47, indicating a statistically significant positive correlation between COVID-19 positivity and MI mortality. The bias risk was examined using a funnel plot, and an I2 value of 78% suggests some underlying bias, likely due to study selection according to the inclusion criteria. Overall, this meta-analysis indicates that further research into the correlation between COVID-19 positivity and MI mortality is vital to consider the points of correlation (inflammatory responses, treatment methods) and the long-term effects of COVID-19 on cardiovascular health.