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Polygence Scholar2024
Samyukta Murthy's profile

Samyukta Murthy

Class of 2025Fremont, California

About

Hello! My name is Samyukta and my Polygence Pods Project is on Neuroscience and Alzheimer’s disease, and I’m going to be learning about the lifestyle factors that increase the risk for this disease. This project is going to help me get a closer understanding of healthcare and neuroscience, topics which have always interested me!

Projects

  • "Antioxidant Therapies to Combat Oxidative Stress in Sensorineural Hearing Loss and Alzheimer's Disease" with mentor Joanna (July 24, 2024)

Project Portfolio

Antioxidant Therapies to Combat Oxidative Stress in Sensorineural Hearing Loss and Alzheimer's Disease

Started June 12, 2024

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Abstract or project description

Hearing loss is closely linked to cognitive decline and neurodegenerative diseases like Alzheimer's disease (AD), with oxidative stress and mitochondrial dysfunction playing key roles in their pathogenesis. Antioxidants such as α-lipoic acid (LA), coenzyme Q10 (CoQ10), NADH, MitoQ, and Szeto Schiller (SS) peptides show promise in mitigating oxidative stress and protecting auditory cells by targeting mitochondrial dysfunction. This review emphasizes the potential of these antioxidants in offering therapeutic benefits for both hearing loss and AD, highlighting their role in reducing oxidative damage and improving cognitive performance.