Saanvi Muthuchetty

Is utilizing recent advancements in diagnostic testing including blood biomarkers, and advanced brain and retinal imaging, more effective in diagnosing Alzheimer’s Disease at an early stage compared to using the current diagnosis method which primarily relies on monitoring mental decline?

Started Jan. 8, 2024

Abstract or project description

Alzheimer’s Disease (AD) is a very common neurodegenerative disorder comprising 60 to 70% of cases of dementia. Researching more effective diagnosis methods for Alzheimer’s is vital because it can provide early diagnosis, timely intervention, and potentially slow disease progression. The current issue with diagnostic approaches lies in the reliance on clinical symptoms and mental decline, which are only present in later stages of AD, hindering proper early treatment. A more effective diagnosis method utilizing recent advancements in diagnostic tests including blood tests for specific markers, brain imaging to observe specific abnormal proteins, along with a revolutionary method of retinal imaging, would obtain the most accurate diagnosis. Using this precocious diagnostic method will not only allow early treatment, but will also help identify patients in early stages of the disease, allowing them to participate in clinical trials for further study. This would improve understanding of the progression of Alzheimer’s and provide opportunity for the development of new, more successful therapies.