Julia Lai

Understanding the Impact of Respiratory Viral Infections on Immunocompromised Populations

Started Nov. 28, 2023

Abstract or project description

Respiratory viral infections like COVID-19, influenza, and respiratory syncytial viruses impact human health tremendously, especially that of immunocompromised people. These individuals have a weakened immune system and, thus, are more vulnerable to catching and developing worse infections. This report contrasts the normal immune response to respiratory infections with the response and impact of viral disease on the immunocompromised. Specifically, it will focus on individuals with autoimmune diseases (systemic lupus erythematosus and type 1 diabetes), chronic diseases that affect the immune system (lymphoma and persistent Epstein-Barr virus infection), and people who fall into high-risk age categories (adults greater than age 65 and infants from 0 to 6 months). The goal is to explore the effects of respiratory viral disease on groups with weakened immunity to identify protective strategies for them in our communities. We propose vaccination and healthcare accessibility as well as strict adherence to public health guidelines and personal preventative measures, as important ways to safeguard our vulnerable population.