Caroline Cho

Mechanism of Botulinum A and Clinical Applications

Started Jan. 19, 2024

Abstract or project description

This project investigates botulinum toxin's molecular mechanisms and clinical applications through Botox injections, focusing on its effects at neuromuscular junctions, acetylcholine release inhibition, and muscle contraction impacts. It examines neurological effects, both therapeutic and adverse, with emphasis on migraine treatment efficacy and potential risks. The study explores Botox's action in blocking pain-causing neuropeptides for migraine relief and its use in treating hyperhidrosis by inhibiting sweat gland acetylcholine release. The research aims to enhance understanding of Botox's physiological impacts, improve patient selection, and increase treatment safety across various clinical applications.