Ashley Peng

How do adverse childhood experiences (ACEs) affect neurological structures and networks, and what role does it play in the development of chronic pain?

Started May 20, 2024

Abstract or project description

My project is an integrative literature review that seeks to explore how childhood trauma impacts the brain’s neurological structures and networks, and how such outcomes further create susceptibility to the development of chronic pain. Drawing from empirical research and theory within neurology, psychiatry, and psychology, this paper will critically examine findings that help answer the aforementioned research question. The literature being reviewed discusses the pain matrix, specifically pertaining to connections with the somatosensory cortex. The current body of neuroscience literature points to how chronic pain impacts the brain structurally and functionally. Likewise, studies have linked similar neurological outcomes to childhood trauma. Notwithstanding, there is limited research on the role that childhood trauma plays in shaping such changes, which may lead to a higher risk of developing chronic pain. Current methodology primarily involves the use of fMRI’s of subjects with chronic pain or complex trauma. Chronic pain is defined as pain that lasts for at least three months following a healed injury that is not further explained by a medical diagnosis, and impacts one's everyday functioning. Childhood trauma is defined as potentially traumatic events including physical, sexual, or emotional abuse, neglect, racism and discrimination, and violence within the household or community.