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Polygence Scholar2024
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Annyesha Auddy
Class of 2025Chantilly, Virginia
About
Projects
- "How do the underlying biochemical processes induce hyperhomocysteinemia which leads to Cerebral Venous Sinus Thrombosis (CVST), especially in young females who are pregnant or postpartum, and what are possible pharmaceuticals that could potentially impede the overproduction of homocysteine upon detection of hyperhomocysteinemia?" with mentor Kathryn (Aug. 1, 2024)
Project Portfolio
How do the underlying biochemical processes induce hyperhomocysteinemia which leads to Cerebral Venous Sinus Thrombosis (CVST), especially in young females who are pregnant or postpartum, and what are possible pharmaceuticals that could potentially impede the overproduction of homocysteine upon detection of hyperhomocysteinemia?
Started Nov. 9, 2023
Abstract or project description
Research Summary: The chemical aspects that lead to hyperhomocysteinemia (excessive homocysteine) How do these chemical aspects connect with the attributes associated with people who are at risk of CVST, young adults (mostly females) and pregnant or postpartum women. Homocysteine is an amino acid, so is there any other chemical substance that could work to control the production of homocysteine in order to prevent hyperhomocysteinemia. CVST affects 1.37 to 2.62 out of 100,000 people in the United States, and women from the ages of 18 to 44 years were reported to have the highest incidence rates.