Amani Multani

Exploring shared neurobiological mechanisms across Bipolar Disorder, schizophrenia, and Autism Spectrum Disorder

Started May 25, 2023

Abstract or project description

Within the mysterious world of the human body, symptoms transcend the normal physical boundaries of several diseases: hypersensitivity, mania, and psychosis. For example, patients with hypersensitivity need to address triggers to adapt to the world comfortably. Similar stages in the development of disorders often arise in bipolar disorder (BD), schizophrenia, and autism spectrum disorder (ASD). All three conditions are highly associated with genetic factors, neurotransmitter imbalances, altered brain structures, and environmental stimuli. Although these conditions share many of the same symptoms and are associated with many of the same possible causes, it is unclear why these diseases share symptoms and how their mechanisms may be interrelated. This review will examine risk factors for development of these disorders and improve our understanding of comorbidity across these disorders about these three diseases.