Advaith Dinesh

The use of phage display and antibodies for the treatment of cancer

Started Nov. 20, 2023

Abstract or project description

Lung cancer kills millions of individuals in the United States each year, yet conventional treatments, such as chemotherapy, lack specificity and kill healthy and cancerous cells alike. In precision medicine, antibody-drug conjugates (ADCs) have arisen as a novel way to fight against cancer, specifically targeting malignant cancer cells. Previous studies have established the foundational principles of ADCs, demonstrating that they can improve target specificity and efficacy. By exploring a medicinal pathway that is different from conventional treatment, scientists may be able to broaden the availability of treatment options for patients fighting cancer. By reviewing a vast collection of articles, this paper gathers relevant and recent information regarding the efficacy, characteristics, and limitations to antibody-drug conjugates. Although variations do exist, most ADCs on the market and preclinical studies display promising results that support its advantageous characteristics; Yet, more research needs to be done to solidify these claims. Shedding light on ADCs may help bring in more funding and awareness dedicated to research of them, which may allow the drug’s advancement to grow. Therefore, it would provide patients the opportunity to extend their lifetime.