Investigating SARS-CoV-2 and the Vaccine’s Global Impact on Cardiac Complications
Project by Polygence alum Himani
Project's result
Research Paper was published at Research Archive for Rising Scholars and I will be sharing my research at the Polygence Symposium in Fall 2024. Additionally, I have shared my findings and research on Medium.
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Summary
The COVID-19 pandemic, initiated by SARS-CoV-2 in early 2020, has profoundly impacted global health, particularly cardiovascular disease (CVD). This research paper examines the link between COVID-19 and CVD, highlighting the increase in CVD rates due to the inflammatory response triggered by the virus. Inflammation affects the heart's lining, muscle, and surrounding tissue, potentially leading to atherosclerosis, where plaque buildup can cause blood clots, heart attacks, and strokes (Heart Disease and Stroke). During SARS-CoV-2 infection, the immune system's pro-inflammatory cytokines exacerbate inflammation, impacting heart function and promoting heart disease. Furthermore, an analysis of data from the Centers for Disease Control and Prevention website CDC Wonder revealed that CVD rates post-COVID-19 increased in 2019-2021. While Oxford-AstraZeneca's vaccine, Vaxzevria, can trigger blood clotting, other studies show that various vaccinations, such as Johnson-Johnson, Pfizer, and Moderna, can reduce cardiovascular complications by decreasing inflammation and infection rates (Paknahad et al. 173).
Gabriel
Polygence mentor
PhD Doctor of Philosophy candidate
Subjects
Biology, Medicine
Expertise
Tumor Immunology, cancer biology, Immunology, Biotechnology
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Himani
Student
Hello! My name is Himani, and my Polygence project is on SARS-CoV-2 and the vaccine's global impact on cardiac complications. I decided to pursue this project because it's crucial to understand certain viruses' impacts on heart disease and how the virus leads to severe inflammation within the heart, causing heart disease. Following the completion of my project, I would like to publish my research paper to the Research Archive for Rising Students and be able to present at the Polygence Symposium Conference.
Graduation Year
2026
Project review
“My overall experience with the research project was excellent! Despite encountering some setbacks, Gabriel provided invaluable support throughout the process. While writing my research paper, I incorporated Gabriel's feedback and dedicated at least one hour daily to my research project. Without this commitment, I wouldn't have been able to construct such a sophisticated research paper.”
About my mentor
“Gabriel is genuinely enthusiastic, helpful, and very intelligent. His diligence and patience throughout my project were incredible! Gabriel addressed any necessary questions post-meeting and helped me plan everything throughout the four months of writing and researching. He provided me with numerous articles of information that benefited my research paper. He also consistently gave me substantial feedback, which eventually strengthened my research paper remarkably. I am grateful to have a mentor like Gabriel and happy I was given a fantastic opportunity to work with him!”
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