Reuben D
- Research Program Mentor
PhD at Brigham Young University
Expertise
Immunology, Antivirals, Blood Diseases, Cancer Biology and Therapeutics, Drug Discovery & Development, Biochemistry, Gene Therapy, Oligonucleotides, Nuclear Medicince
Bio
I am a Research Scientist at Purdue University. I research and supervise the investigation of diseases of the human body and how they can be understood and treated. Specifically, I am conducting active research on cancers, RSV and sickle cell disease. I have a Bachelors in Chemistry with a Minor in Biology. My PhD was in Medicinal Chemistry, which focuses on the design and development of drug therapies for diseases of the human body. I was a Postdoctoral Associate at Purdue University. The therapeutic areas of my research include gene therapy, immunology, radiotherapy, CAR-T cell therapy, antivirals, antibacterials, and antiparasitics. When I am not at work, I like to build Legos, hike with my dog or go to the gym!Project ideas
Genetic markers for the diagnosis and treatment of Sickle Cell Disease
This project highlights the genetic differences between healthy and patients with sickle cell disease. The genetic drivers and the effects of the genetic differences will be highlighted. Additionally, the downstream molecular targets from these genetic differences will be reviewed and discussed as potential therapeutic targets. The therapies discussed include gene therapy, monoclonal antibodies and small molecule drugs.
Radioligands and their utility as diagnostic and therapeutic agents for cancers.
The physics and chemistry of radio nucleotides will be discussed. This discussion will lead to the appropriate application in imaging and cell killing as treatments for cancers. Examples of drugs utilizing radioligands will be discussed, their synthesis and pharmacokinetics and pharmacodynamic properties will be expounded upon. The molecular effects of using radioligand will be discussed as well. Suggestions as to future developments and potential advancements will be proposed.
The Role of AI in the generation of targeted therapeutics
An article exploring targeted therapeutics, it’s benefit and how AI can expedite the process of identification of disease-related molecular targets as well as generate target-specific warheads in pharmaceuticals.